Norovirus Hits Florida Hard

Across Florida, 61 clusters of norovirus were identified during January and February. That's up from 47 clusters in 2009.  Places where the virus can spread easily includes jails, schools and assisted living facilities.

Most healthy people survive Norovirus just fine, with recovery in about two days. Those who do come down with it are contagious for three days after they start feeling well.

Preventing the spread of the virus means hand-washing, proper food handling, and for those who are sick, staying home.

Effects of technological processes on the tenacity and inactivation of norovirus GGII in experimentally contaminated foods

American Society for Microbiology
Sascha Mormann, Mareike Dabisch, and Barbara Becker

Abstract

Contaminated food is a significant vehicle of human norovirus transmission. The present study determined the effect of physicochemical treatments on the tenacity of infective human norovirus genogroup II in selected foods. Artificially contaminated produce was subjected to a selection of processes used by the food industry for preservation and by the consumer for storage and preparation. Virus recovery was carried out by ultrafiltration and monitored with bacteriophage MS2 as an internal process control. Norovirus was quantified with monoplex one-step TaqMan real-time RT-PCR and an external standard curve based on recombinant RNA standards. A RNase pretreatment step was introduced to avoid false-positive PCR results caused by accessible RNA allowing the detection of intact virus particles. Significant titer reductions were obtained with heat treatments usually applied by the consumer for food preparation (baking, cooking, roasting). Generally, processes for preservation and storage, such as cooling, freezing, acidification ( pH 4.5) and moderate heat treatments (pasteurization) appear to be insufficient to inactivate norovirus within a food matrix or on the surface. Beside the persistence in processed food, this study provides comparable data about individual matrix-specific protective effects, recovery rates and inhibitory influences on the PCR reactions. The established workflow might be applied to other non-cultivable enteric RNA viruses which are connected to foodborne diseases. The obtained data of this project may also benefit the process optimization for norovirus inactivation in food by adjusting food processing technologies and promote the development of risk assessment systems in order to improve the consumer protection.

Norovirus: An Ongoing Challenge

25 November 2009

28 Portland Place, London, W1B 1DE

Tab 1: Conference overview

Norovirus outbreaks remain a major public health concern and the subject of much media attention.

It is estimated that Norovirus accounts for 50% of worldwide food borne gastroenteritis (diarrhoea and vomiting) outbreaks and causes more than 23 million cases of acute gastroenteritis a year in the USA alone. It is also the most prevalent cause of infectious gastroenteritis in England and Wales – and is now recognised to occur throughout the year and affect individuals of any age.

Norovirus used to be known as the ‘winter vomiting virus’, but now could claim the title of the ‘cruise ship bug’, given it’s prolificacy in that environment. Norovirus is also known for its dominance of the gastrointestinal infection statistics and its ability to close down hospital wards or hotels when it strikes.

With the continuing difficulties involved in controlling outbreaks of Norovirus, this conference will share experiences and update delegates on current knowledge of the virus and managing outbreaks, both in clinical and community settings.

The conference will be chaired by Professor Rodney Cartwright, Medical Microbiologist and RSPH advisor.

Who should attend?

This meeting will provide an excellent opportunity to update on the issues surrounding Norovirus infection and outbreak. It is essential learning for those working in the health sector, environmental health, the cleaning products industry, the cruise ship industry and anyone working in infection control.

For more information, please contact Jennifer Tatman, Conference and Event Officer on 020 3177 1614 or jtatman@rsph.org.uk.

Norovirus 101--Here's What We All Really Need To Know!

 Mark Roberts is a Texas-based insurance sales and marketing agent who doubles as a pretty decent health writer.  In the Cypress Times, he takes a "just the facts" approach to laying out what we all need to know about Norovirus.  A few examples:

The norovirus is known to be highly contagious; and, therefore, the illness can literally be passed around like a big bag of chips in a hurry.

Actually, according to GuideToCaribbeanVacations.com, these are a group of related viruses, referred to as "Norwalk-like viruses" or NLV, causing acute gastroenteritis in humans. The incubation period is usually between 24 and 48 hours although cases have been reported to occur within 12 hours of exposure. Symptoms are vomiting, diarrhea with abdominal cramps and nausea generally lasting 24 to 60 hours. Dehydration is the most common complication. Yet even during the worst, most publicized outbreaks of sick ship only a small percentage of passengers are usually affected. According to Princess Cruises, "Statistics have shown that the chance of contracting Norovirus on land is 1 in 12; and 1 in 4000 on a cruise ship."

According to the Minnesota Department of Health, Noroviruses are members of a group of viruses called caliciviruses, also known previously as “Norwalk-like viruses.” Norovirus is also called viral gastroenteritis, food poisoning, and calicivirus. Norovirus infection causes gastroenteritis, which is an inflammation of the stomach and the small and large intestines. And, Norovirus is by far the leading cause of foodborne illness outbreaks. This infection is often mistakenly referred to as the “stomach flu"- it is not related to the flu (influenza), which is a respiratory illness caused by influenza virus. Norovirus is not a “new” virus, but interest in it is growing as more is learned about how frequently noroviruses cause illness in people.

Read the rest in The Cypress Times.

Spanish Study Finds Norovirus A Principal Definable Cause of Foodborne Illness

A study by the University Hospital in Albacete, Spain finds that noroviruses were the principal definable causes of foodborne illnesses.  

Norovirus commonly causes pediatric diarrhea in the region of Spain where the hospital is located. The study found the role of noroviruses in mixed infections requires additional study.

Three years of data, covering 2005-08, shows norovirus was the second most common agent implicated in acute sporadic episodes of gastroenteritis in children under age 5 who required hospitalization.

“Clinical and epidemiological characteristics of norovirus severe infection in children are not so well established and identifying the clinical profile of this infection would be useful because of the absence of rapid and widely-available detection methods in clinical laboratories, “ says the study report.

Norovirus was detected in 17.3 percent of the 221 study participants. Some of the characteristics researchers noted include:

  • Norovirus was present in 52.5 percent of 32 patients with mixed infections and was identified as the single etiological pathogen in 8.2 percent.
  • The most common symptoms were vomiting and fever.
  • The typical hospital stay was 3.5 days.
  • Norovirus affected mostly children under age 2.

More can be found in Infectious Diseases in Children.

What is Norovirus?

About Norovirus

The Centers for Disease Control and Prevention (CDC) estimates that noroviruses cause 23 million cases of acute gastroenteritis annually, making noroviruses the leading cause of gastroenteritis in the United States (CDC, 2006; Fankhauser, et al., 2002; Mead, et al., 1999).

Of viruses, only the common cold is reported more often than viral gastroenteritis (norovirus) (Benson & Merano, 1998).

Nature has created an ingenious bug in norovirus. The round blue ball structure of norovirus is actually a protein surrounding the virus’s genetic material. The virus attaches to the outside of cells lining the intestine, and then transfers its genetic material into those cells. Once the genetic material has been transferred, norovirus reproduces, finally killing the human cells and releasing new copies of itself that attach to more cells of the intestine’s lining.

Norovirus (previously called “Norwalk-like virus” or NLV) is a member of the family Caliciviridae. The name derives from the Latin for chilice—calyx—meaning cup-like, and refers to the indentations of the virus surface.

The family of Caliciviridae consists of several distinct groups of viruses that were first named after the places where outbreaks occurred. The first such outbreak occurred in 1968 among schoolchildren in Norwalk, Ohio (Glass, et al., 2000).  The prototype strain was identified four years later, in 1972, and was the first virus identified that specifically caused gastroenteritis in humans (Glass, et al., 2000).

Other discoveries followed, with each strain name based on the location of its discovery-location, e.g., Montgomery County, Snow Mountain, Mexico, Hawaii, Parmatta, Taunton, and Toronto viruses. A study published in 1977 found that the Toronto virus was the second most common cause of gastroenteritis in children (Middleton, Szmanski & Petric, 1977).

Eventually this confusing nomenclature was rsolved, first in favor of calling each of the strains a Norwalk-like virus, and then simply, a norovirus – the term used today.
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"Norovirus" Makes It Into Merriam-Webster's Collegiate Dictionary

The word "Norovirus" has been added to the new Merriam-Webster Collegiate Dictionary. Its one of about 100 "new" words recognized by the folks at Merriam-Webster.

Norovirus, according to Merriam-Webster, is any of a genus of small round single-stranded RNA viruses: specifically, the Norwalk Virus.

Merriam-Werbster added 100 new words this year, some reflect current events, like "dirty bomb" and "Norovirus." Others define new technology or products, such as "infinity pool." That's an outdoor pool with an edge designed to make water appear to flow into the horizon.

Probably won't be long before Norovirus is accepted as a correctly spelled word on your computer!

About Norovirus


Noroviruses are estimated to cause 23 million cases of acute gastroenteritis (commonly called the "stomach flu") in the U.S. each year, and are the leading cause of gastroenteritis. Of viruses, only the common cold is reported more often than viral gastroenteritis (norovirus).

Noroviruses may cause more outbreaks of foodborne illness than all bacteria and parasites. They can cause extended outbreaks because of their high infectivity, persistence in the environment, resistance to common disinfectants, and difficulty in controlling their transmission through routine sanitary measures.

The norovirus is transmitted primarily through the fecal-oral route and fewer than 100 norovirus particles are said to be needed to cause infection. Transmission occurs either person-to-person or through contamination of food or water. Transmission can occur by touching surfaces or objects contaminated with norovirus and then placing that hand in your mouth; having direct contact with another person who is infected and showing symptoms; sharing foods or eating utensils with someone who is ill; exposure to aerosolized vomit; and consuming food contaminated by an infected food handler.

The virus is shed in large numbers in the vomit and stool of infected individuals, most commonly while they are ill. Some individuals may continue to shed norovirus up to two weeks after they have recovered from the illness.

Symptoms of Norovirus infection

Usual symptoms of norovirus infections include nausea, vomiting, diarrhea, and abdominal pain. Headache and low-grade fever may also accompany this infection. The illness is usually mild and brief. It will develop 24 to 48 hours after exposure and lasts for 24 to 60 hours. Recovery usually occurs in two to three days without serious or long-term health effects. Immunity is not permanent and reinfection can occur.

Diagnosis and treatment for Norovirus

Laboratory diagnosis is difficult. Diagnosis is often based on the combination of symptoms, particularly the prominence of vomiting, little fever, and the short duration of illness. Actual proof of infection requires research laboratory techniques in which norovirus particles are identified by electron microscopy from samples of stool or vomitus.

No specific treatment is available. Persons who are severely dehydrated might need rehydration therapy.

Preventing Norovirus infection

The good news about norovirus is that it does not multiply in foods as many bacteria do. In addition, thorough cooking destroys this virus. To avoid this illness, make sure the food you eat is cooked completely. Shellfish (oysters, clams, mussels) pose the greatest risk and any particular serving may be contaminated; there is no way to detect a contaminated oyster from a safe oyster. With shellfish, only complete cooking offers reliable protection.

Wash raw vegetables thoroughly before eating or preparing salads. If you are traveling in an area that appears to have polluted water, drink only boiled drinks or carbonated bottled beverages without ice.

Wash hands with soap and warm water after using the toilet, before preparing or eating food; and after caring for the sick; exclude persons with gastroenteritis from the kitchen; and always dispose of sewage in a sanitary manner.

About Norovirus

Noroviruses are estimated to cause 23 million cases of acute gastroenteritis (commonly called the ěstomach fluî) in the U.S. each year, and are the leading cause of gastroenteritis. Of viruses, only the common cold is reported more often than viral gastroenteritis (norovirus).

Noroviruses may cause more outbreaks of foodborne illness than all bacteria and parasites. They can cause extended outbreaks because of their high infectivity, persistence in the environment, resistance to common disinfectants, and difficulty in controlling their transmission through routine sanitary measures.

The norovirus is transmitted primarily through the fecal-oral route and fewer than 100 norovirus particles are said to be needed to cause infection. Transmission occurs either person-to-person or through contamination of food or water. Transmission can occur by touching surfaces or objects contaminated with norovirus and then placing that hand in your mouth; having direct contact with another person who is infected and showing symptoms; sharing foods or eating utensils with someone who is ill; exposure to aerosolized vomit; and consuming food contaminated by an infected food handler.

The virus is shed in large numbers in the vomit and stool of infected individuals, most commonly while they are ill. Some individuals may continue to shed norovirus up to two weeks after they have recovered from the illness.

Symptoms of Norovirus infection

Usual symptoms of norovirus infections include nausea, vomiting, diarrhea, and abdominal pain. Headache and low-grade fever may also accompany this infection. The illness is usually mild and brief. It will develop 24 to 48 hours after exposure and lasts for 24 to 60 hours. Recovery usually occurs in two to three days without serious or long-term health effects. Immunity is not permanent and reinfection can occur.

Diagnosis and treatment for Norovirus

Laboratory diagnosis is difficult. Diagnosis is often based on the combination of symptoms, particularly the prominence of vomiting, little fever, and the short duration of illness. Actual proof of infection requires research laboratory techniques in which norovirus particles are identified by electron microscopy from samples of stool or vomitus.

No specific treatment is available. Persons who are severely dehydrated might need rehydration therapy.

Preventing Norovirus infection


The good news about norovirus is that it does not multiply in foods as many bacteria do. In addition, thorough cooking destroys this virus. To avoid this illness, make sure the food you eat is cooked completely. Shellfish (oysters, clams, mussels) pose the greatest risk and any particular serving may be contaminated; there is no way to detect a contaminated oyster from a safe oyster. With shellfish, only complete cooking offers reliable protection.

Wash raw vegetables thoroughly before eating or preparing salads. If you are traveling in an area that appears to have polluted water, drink only boiled drinks or carbonated bottled beverages without ice.

Wash hands with soap and warm water after using the toilet, before preparing or eating food; and after caring for the sick; exclude persons with gastroenteritis from the kitchen; and always dispose of sewage in a sanitary manner.